A Case of Eosinophilic Pustular Folliculitis (Ofuji’s Disease) in a Newborn

ji’s disease is an inflammatory dermatosis which was first described in 1970 by Ofuji et al1. The eruption of EPF consists of follicular papules and pustules that tend to form an annular configuration mimicking fungal infections. The histopathologic feature of EPF is characterized by perifollicular inflammatory cellular infiltration featuring numerous eosinophils and some mononuclear cells1. Since the first report by Ofuji et al.1, there have been numerous case reports of EPF worldwide; however, its pathophysiology remains unclear. In 1984, Lucky et al.2 first described five children with EPF. Those pediatric cases were characterized by recurrent crops of sterile pustules on the scalp, trunk and extremities with the distinctive feature that in children the lesions did not form the characteristic polycyclic rings found in adults. Since then in only a few instances has EPF been described in infants and children. In 1986, Soeprono and Schinella3 described three cases of EPF in patients with acquired immunodeficiency syndrome. EPF seen in patients with human immunodeficiency virus infection is clinically distinct from classical EPF first described by Ofuji et al., therefore Moritz and Elmets4 once proposed to classify EPF into classical, HIV-associated, and infantile type. We describe a case of EPF occurring in a neonate.